CHEM 253 Quantitative Analysis*

The lecture includes a comprehensive study of the principles and techniques of the laboratory procedures as well as the theoretical basis of gravimetric, volumetric, and instrumental analysis. The laboratory consists of a series of quantitative determinations of elemental unknowns by classical and instrumental methods.

Credits

5 Credits

Prerequisite

CHEM 112 and MATH 143

Corequisite

CHEM 253L

CHEM 253Quantitative Analysis*

Please note: This is not a course syllabus. A course syllabus is unique to a particular section of a course by instructor. This curriculum guide provides general information about a course.

I. General Information

Department

Physical Science

II. Course Specification

Course Type

Program Requirement

Credit Hours Narrative

5 Credits

Semester Contact Hours Lecture

45

Semester Contact Hours Lab

90

Semester Contact Hours Clinical

NA

Prerequisite Narrative

CHEM 112 and MATH 143

Corequisite Narrative

CHEM 253L

Grading Method

Letter grade

Repeatable

N

III. Catalog Course Description

The lecture includes a comprehensive study of the principles and techniques of the laboratory procedures as well as the theoretical basis of gravimetric, volumetric, and instrumental analysis. The laboratory consists of a series of quantitative determinations of elemental unknowns by classical and instrumental methods.

IV. Student Learning Outcomes

Upon completion of this course, a student will be able to:

CHEM 253 CLASS PORTION OF THE COURSE By the end of the semester, the student should be able to demonstrate: General fundamental understanding of statistical calculations involved in data analysis and reduction including rejection of data and comparison of data sets; General fundamental understanding of the terminology and application of various quality control parameters that might be used in a laboratory and the limits and advantages of each; General fundamental understanding of the various types of errors such as systemnatic and random errorsin ovlved in chemical analysis as well as how to test for and correct such errors when they occur; General fundamental understanding of unit conversions, solution preparation, and glassware calibration as might be used in a chemical laboratory; General fundamental understanding of the preparation, use and data analyses involved in calibration curves; General Fundamental understanding of various types of laboratory notebooks as well as use of external and internal chain of custodies; General fundamental understanding of activity coefficients and ionic strength and how it impacts the chemical measurement process; General fundamental understanding of the classical wet chemical methods of gravimetric analysis, acid-base analysis, oxidation-reduction analysis and compleximetric analysis; General fundamental concepts of analysis involving macromolecular, Supermolecular, and Nanoscale (MSN) systems; Basic understanding of the principles of operation and data analysis for instrumental methods of analysis including most of (but not limited to) the following: UV-visible spectrophotometry, various chromatographic techniques, mass spectroscopy, atomic spectroscopy including plasma spectroscopy. CHEM 253 LABORATORY PORTION OF THE CLASS: At the end of the laboratory portion of the course, the student will be able to demonstrate the ability to: The overall purpose is to show the ability to perform laboratory experiments that are precise and accurate and follow good laboratory practices in the handling, use and disposal of all chemicals used in the laboratory; Calibrate glassware as a function of temperature and volume; Work safely and neatly in a laboratory following all applicable rules for use of chemicals and proper documentation of lab results include laboratory notebooks, reports and chain-of-custody documents; Demonstrate understanding of the use and role of different types of glassware and equipment in the lab by making proper selections of equipment with which to perform the experiment when only generalized directions are given; Demonstrate ability to perform at least three of the classical methods of analysis (see "h" in the class portion of the course criteria immediately above as evidenced by experiments performed within acceptable accuracy and precision requirements as stated by the instructor ; Demonstrate mastery of all calculations used in the laboratory for data analysis and data evaluation; Show general understanding in the data analysis from the types of instrumental methods that are covered in class as listed in part "j" above in the class portion discussion as evidenced by analysis of samples either analyzed by the student, analyzed by the instructor and presented to the student, or obtained from literature sources when appropriate equipment is not available. Should be able to prepare a laboratory report that meets the specified criteria for each experiment as outlined by the instructor. These reports may vary from short data summary reports to full length reports such as might be prepared for publication. The instructor may use a variety of report formats during the course of the semester; At least one experiment should have an emphasis on nanoscale chemistry as recommended by the American Chemical Society and might include an experiment from any one of the following topics; size exclusion chromatography, DSC, TGA, molecular weight by functional group titration, size determination by light scattering, pyrolysis chromatography, x-ray methods, or analysis of nano-scale structure using microscopes and microprobes. Should be able to use a spreadsheet format for all types of data reduction and data presentation; Should be able to understand the meaning of limit of detection and sensitivity as it applies to analytical chemistry and determine the limit of detection and sensitifity for at least one of the pieces of equipment used during the course of the semester.

V. Topical Outline (Course Content)

A course in quantitative analysis should cover the following concepts. Some concepts may be only covered in minor detail and some in significant detail depending on the instructor. Chemical apparatus and unit operations Spreadsheets Random and systematic errors Statistical treatment of data Standardization and calibration Gravimetric methods of analysis Acid base methods of analysis Complex acid base titrations Compleximetric and or precipitation methods of analysis Oxidation reduction titrations Potentiometry Analysis of nano-scale materials Molecular spectroscopy Atomic spectroscopy Mass spectrometry Gas chromatography High performance liquid chromatography Miscellaneous separation methods

VI. Delivery Methodologies

Required Assignments

CHEM 253 CLASS Homework as applicable should be assigned from each major topic as outlined in the CLASS LEARNING OUTCOMES given above. A particular homework assignment may cover one or more of the topics. The assignments should constitute at least 10% of the overall CHEM 253 grade. CHEM 253 LABORATORY The CHEM 253 lab should meet for 6 hours per week. This can be done as 1 lab of 6 hours in length or 2 labs of 3 hours in length at the discretion of the instructor. It is assumed that the majority of the experiments performed in CHEM 253 will take 6 hours to perform and some may take 9 or 12 hours. The number of experiments performed should be at least 10 and should cover the topics listed in the LAB LEARNING OUTCOMES as given above. An individual experiment may cover multiple topics. For example an acid base titration can also include data analysis and spreadsheet components. The CHEM 253 laboratory should constitute at least 40% of the total grade for CHEM 253.

Required Exams

CHEM 253 CLASS A minimum of three exams should be given during the semester in addition to a comprehensive final exam. Because the CHEM 253 class is traditionally small, the administration of the American Chemical Society Standardized exam is not required since statistics on small sample sizes are not meaningful. Exams may be open book, closed, book, in class, in testing center, or take home and different formats may be used for different exams during the course of het semester. The Final exam should constitute at least 10% of the total grade for CHEM 253.

Required Text

No specified single textbook is required but the textbook should be of national prominence such as the quantitative analysis books authored by Harris or Skoog and West.

Required Materials

See required tools.

Required Activities

There are no required activities other than the assignments, exams, and laboratory exercises as outlined above.

Assessment Strategy Narrative

Required outcomes assessment will include the following: Exams Homework Laboratory experiments Final exam CSI on-line evaluation

Specific Course Activity Assignment or Assessment Requirements

CHEM 253 CLASS Homework as applicable should be assigned from each major topic as outlined in the CLASS LEARNING OUTCOMES given above. A particular homework assignment may cover one or more of the topics. The assignments should constitute at least 10% of the overall CHEM 253 grade. CHEM 253 LABORATORY The CHEM 253 lab should meet for 6 hours per week. This can be done as 1 lab of 6 hours in length or 2 labs of 3 hours in length at the discretion of the instructor. It is assumed that the majority of the experiments performed in CHEM 253 will take 6 hours to perform and some may take 9 or 12 hours. The number of experiments performed should be at least 10 and should cover the topics listed in the LAB LEARNING OUTCOMES as given above. An individual experiment may cover multiple topics. For example an acid base titration can also include data analysis and spreadsheet components. The CHEM 253 laboratory should constitute at least 40% of the total grade for CHEM 253. CHEM 253 CLASS A minimum of three exams should be given during the semester in addition to a comprehensive final exam. Because the CHEM 253 class is traditionally small, the administration of the American Chemical Society Standardized exam is not required since statistics on small sample sizes are not meaningful. Exams may be open book, closed, book, in class, in testing center, or take home and different formats may be used for different exams during the course of het semester. The Final exam should constitute at least 10% of the total grade for CHEM 253. There are no required activities other than the assignments, exams, and laboratory exercises as outlined above.