MLTE 222 Basic Concepts in Transfusion Medicine

This course is an introduction to the basic theory and concepts of antigen-antibody reaction as they pertain to blood cell transfusions. Blood group antigens and the genetics of their inheritance are examined. Methods are introduced for performing blood grouping, compatibility testing, and component selection.

Semester Contact Hours Lecture

60

Semester Contact Hours Lab

0

MLTE 222Basic Concepts in Transfusion Medicine

Please note: This is not a course syllabus. A course syllabus is unique to a particular section of a course by instructor. This curriculum guide provides general information about a course.

I. General Information

Department

II. Course Specification

Course Type

{D7A8FC71-978F-4003-9933-512C476323B2}

Semester Contact Hours Lecture

60

Semester Contact Hours Lab

0

III. Catalog Course Description

This course is an introduction to the basic theory and concepts of antigen-antibody reaction as they pertain to blood cell transfusions. Blood group antigens and the genetics of their inheritance are examined. Methods are introduced for performing blood grouping, compatibility testing, and component selection.

IV. Student Learning Outcomes

Upon completion of this course, a student will be able to:

• Identify the antigens and antibodies of the ABO and Rh systems based on serologic results.
• Determine genetic ABO phenotypes based on possible ABO genotypes.
• Identify ABO discrepancies and provide suggestions as to its resolve.
• Identify major antigens and antibodies within the Kell, Duffy, Kidd, MNSs, Lewis, P, I, and Lutheran blood groups.
• Know the purpose of and be able to detect and identify unexpected antibodies using antibody screens and antibody panels respectively.
• Select appropriate blood selection for transfusion and what to do if compatible blood cannot be located.
• Discuss the steps in blood issuing to include documentation and visual inspection.
• Identify transfusion reactions; acute hemolytic, no hemolytic and delayed.
• Describe the role and responsibilities of medical personnel in the event of an adverse reaction.
• Perform and discuss tests routinely performed on cord blood cells when hemolytic disease of the newborn is suspected.
• List special considerations that must be met when selecting blood for exchange transfusion and intrauterine transfusion and explain the purpose of each requirement.
• Apply prior knowledge to problem solving including recognizing abnormal or unusual test results, recognizing unacceptable quality control results, and applying knowledge of established procedures to verify results.
• Correlate blood bank findings with those generated in other areas of the clinical laboratory, patient symptoms and clinical history, to make appropriate and effective on-the-job professional decisions.
• Demonstrate accurate/effective psychomotor skills in student lab and internship by utilizing the information from this course.

V. Topical Outline (Course Content)

VI. Delivery Methodologies